Pregnancy Cat

Pancreatin should be given to a pregnant woman only if clearly needed. It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Pancreatin is administered to a nursing mother.

Precautions

Patients known to be allergic to animal protein should be treated with caution.

Overdose Effects

Excessive dosage may produce a laxative effect. Systemic toxicity does not occur. Very high dosage may cause hyperuricaemia and hyperuricosuria

Drug Classes

Digestive Enzyme

Storage Conditions

Keep all medicines out of reach of children. Store in a cool and dry place, protected from light.

Composition

Each enteric film-coated tablet contains 325 mg of Pancreatin BP that provides not less than the following enzymatic activity-

Amylase 7800 units
Protease 455 units
Lipase 6500 units

Mode Of Action

Pancreatin is a preparation of Pancreatin, an extract from mammalian pancreas containing enzymes with Amylase, Protease and Lipase activity. It is designed to disintegrate in the alkaline medium of the duodenum where it releases the active enzyme components of Pancreatin (Amylase, Protease and Lipase). Amylase hydrolyzes dietary starch to yield maltose, maltoriose and a-dextrin. Protease cleaves peptide bonds in the center of proteins and polypeptides and forms amino acids and oligopeptides. Lipase hydrolyzes dietary triglycerides forming two molecules of fatty acid and a molecule of beta-monoglyceride. It converts not less than 25 times its weight of starch into soluble carbohydrates and not less than 25 times its weight of casein into proteoses within 5 mins, (equivalent to 150 times in 30 mins).

Reconstitution

n/a